US 11,725,023 B2
Therapeutic oligonucleotides
Heather O'Neill, Mesa, AZ (US); Günter Mayer, Bonn (DE); Mark Miglarese, Phoenix, AZ (US); and David Spetzler, Paradise Valley, AZ (US)
Assigned to Caris Science, Inc., Irving, TX (US)
Filed by Caris Science, Inc., Irving, TX (US)
Filed on Feb. 3, 2021, as Appl. No. 17/166,071.
Application 17/166,071 is a continuation of application No. 15/745,407, granted, now 10,941,176, previously published as PCT/US2016/044595, filed on Jul. 28, 2016.
Claims priority of provisional application 62/305,536, filed on Mar. 9, 2016.
Claims priority of provisional application 62/269,671, filed on Dec. 18, 2015.
Claims priority of provisional application 62/239,226, filed on Oct. 8, 2015.
Claims priority of provisional application 62/220,652, filed on Sep. 18, 2015.
Claims priority of provisional application 62/198,051, filed on Jul. 28, 2015.
Claims priority of provisional application 62/198,110, filed on Jul. 28, 2015.
Prior Publication US 2022/0356203 A1, Nov. 10, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. C12N 15/115 (2010.01); C07H 19/173 (2006.01); A61K 47/69 (2017.01); A61P 37/00 (2006.01); A61P 25/28 (2006.01); A61P 31/00 (2006.01); A61P 9/00 (2006.01); A61P 35/02 (2006.01); A61P 29/00 (2006.01); A61K 9/00 (2006.01); C07H 19/09 (2006.01); C07H 19/19 (2006.01); C07H 21/00 (2006.01); C12N 15/10 (2006.01); C12Q 1/6886 (2018.01); G06T 7/00 (2017.01); G01N 33/574 (2006.01); G01N 33/53 (2006.01); G01N 33/68 (2006.01)
CPC C07H 19/173 (2013.01) [A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 47/6911 (2017.08); A61K 47/6929 (2017.08); A61P 9/00 (2018.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); A61P 31/00 (2018.01); A61P 35/02 (2018.01); A61P 37/00 (2018.01); C07H 19/09 (2013.01); C07H 19/19 (2013.01); C07H 21/00 (2013.01); C12N 15/10 (2013.01); C12N 15/115 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5308 (2013.01); G01N 33/57484 (2013.01); G01N 33/68 (2013.01); G06T 7/0012 (2013.01); C12N 2310/16 (2013.01); C12N 2320/10 (2013.01); C12Q 2600/158 (2013.01)] 14 Claims
 
1. An oligonucleotide consisting of SEQ ID NO. 4357.