CPC C07D 231/08 (2013.01) [C07C 209/36 (2013.01); C07C 2603/10 (2017.05)] | 11 Claims |
1. A process of preparing N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide or a salt thereof, comprising the step of contacting 1-isopropyl-3-(alkoxycarbonylaminosulfonyl)-1H-pyrazole with 1,2,3,5,6,7-hexahydro-s-indacen-4-amine in the presence of a solvent to obtain N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide:
wherein R is C1-6 alkyl.
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