US 11,724,986 B2
Crystalline solid forms of N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, processes for making, and methods of use
Dana T. Aftab, San Rafael, CA (US); Nathan Guz, Half Moon Bay, CA (US); Stephen Lau, South San Francisco, CA (US); Noel Hamill, Belfast (GB); Tracy Walker, Lurgan (GB); Jana Galbraith, Kinallen (GB); Simon Yau, Sunnyvale, CA (US); and Khalid Shah, Half Moon Bay, CA (US)
Filed by Exelixis, Inc., Alameda, CA (US)
Filed on Oct. 29, 2020, as Appl. No. 17/84,312.
Application 17/084,312 is a division of application No. 16/671,834, filed on Nov. 1, 2019, granted, now 10,851,061.
Application 16/671,834 is a division of application No. 15/118,738, granted, now 10,501,418, issued on Dec. 10, 2019, previously published as PCT/US2015/016052, filed on Feb. 16, 2015.
Claims priority of provisional application 61/939,985, filed on Feb. 14, 2014.
Prior Publication US 2021/0198205 A1, Jul. 1, 2021
Int. Cl. C07D 215/233 (2006.01); C07D 215/22 (2006.01)
CPC C07D 215/233 (2013.01) [C07D 215/22 (2013.01); C07B 2200/13 (2013.01)] 4 Claims
 
1. A crystalline solid form of Compound 1:

OG Complex Work Unit Chemistry
wherein said crystalline solid form is in Form XXX, wherein said Form XXX is characterized by an x-ray powder diffraction pattern (CuKα) comprising peaks at 7.2, 7.5, 10.0, 12.0, 12.4, 13.5, 15.8, and 19.8 (° 2θ±0.2 ° 2θ) at room temperature.