US 11,724,129 B2
Method for optimizing radiation beam intensity profile shape using dual multiple aperture devices
Joseph Webster Stayman, Baltimore, MD (US); Aswin John Mathews, Baltimore, MD (US); and Reuven Levinson, Haifa (IL)
Assigned to THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US)
Filed by THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US); and Koninklijke Philips NV., Eindhoven (NL)
Filed on Dec. 8, 2021, as Appl. No. 17/545,030.
Application 17/545,030 is a continuation of application No. 15/639,044, filed on Jun. 30, 2017, abandoned.
Claims priority of provisional application 62/356,690, filed on Jun. 30, 2016.
Prior Publication US 2022/0088417 A1, Mar. 24, 2022
Int. Cl. A61N 5/10 (2006.01); G01N 23/00 (2006.01); G21K 1/10 (2006.01)
CPC A61N 5/1077 (2013.01) [G01N 23/00 (2013.01); G21K 1/10 (2013.01); G01N 2223/316 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A device for beam shaping in imaging comprising:
two or more multiple aperture devices placed in series between an x-ray source and a subject, wherein each of the multiple aperture devices have a design and each of the multiple aperture devices are configured to have motion relative to others of the multiple aperture devices and each of the multiple aperture devices comprise a plurality of bars having variable widths and spacings;
wherein the design and the motion of the multiple aperture devices are predetermined to generate a predetermined fluence pattern or the motion of the multiple aperture devices is determined on-the-fly to generate the predetermined fluence pattern; and
a non-transitory computer readable medium programmed for determining the design of each of the multiple aperture devices to achieve the predetermined fluence pattern, and programmed for control and actuation of relative motion between the two or more multiple aperture devices, wherein control and actuation comprises determining a spacing and position of the multiple aperture devices with respect to one another and with respect to a beam to be shaped in order to generate the predetermined fluence pattern.