CPC A61K 51/088 (2013.01) [A61K 51/0478 (2013.01); A61K 51/082 (2013.01)] | 18 Claims |
1. A stabilized non-radioactive kit for the preparation of a 99mTc-maraciclatide radiopharmaceutical composition, said kit comprising:
(a) maraciclatide;
(b) para-aminobenzoic acid sodium salt in an amount between 100 to 600 μg;
(c) stannous chloride dihydrate;
(d) methylene diphosphonic acid;
(e) a buffer comprising sodium hydrogen carbonate in an amount of approximately 1800 μg; and
wherein all the components of said kit are lyophilized and stored in a single container; and
wherein the components are present in an amount such that reconstitution in sterile water for injection produces a composition with a pH between 6.5 and 9.5.
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