US 11,723,960 B2
Compositions and methods for treating gluten intolerance and disorders arising therefrom
David C. Schriemer, Chestermere (CA); and Martial Rey, Paris (FR)
Assigned to Codexis, Inc., Redwood City, CA (US)
Filed by Codexis, Inc., Redwood City, CA (US)
Filed on Feb. 22, 2021, as Appl. No. 17/181,924.
Application 17/181,924 is a division of application No. 15/906,972, filed on Feb. 27, 2018, granted, now 10,960,059.
Application 15/906,972 is a continuation of application No. 14/741,396, filed on Jun. 16, 2015, abandoned.
Claims priority of provisional application 62/118,396, filed on Feb. 19, 2015.
Claims priority of provisional application 62/012,865, filed on Jun. 16, 2014.
Prior Publication US 2021/0220451 A1, Jul. 22, 2021
Int. Cl. A61K 38/48 (2006.01); A61K 36/185 (2006.01)
CPC A61K 38/488 (2013.01) [A61K 36/185 (2013.01); A61K 38/48 (2013.01); C12Y 304/00 (2013.01); C12Y 304/23012 (2013.01)] 20 Claims
 
1. A method for attenuating or preventing intestinal inflammation arising from the presence of peptidic food antigens in a patient in need thereof, which method comprises administering to the patient an effective amount of a pharmaceutical composition comprising neprosin so as to cleave said peptidic food antigens to attenuate or prevent said intestinal inflammation.