CPC A61K 9/5057 (2013.01) [A61K 9/0056 (2013.01); A61K 9/2081 (2013.01); A61K 9/501 (2013.01); A61K 9/5031 (2013.01); A61K 9/5036 (2013.01); A61K 9/5042 (2013.01); A61K 9/5052 (2013.01); A61K 31/167 (2013.01); A61K 31/192 (2013.01); A61K 31/4402 (2013.01); A61K 31/451 (2013.01); A61K 31/522 (2013.01)] | 13 Claims |
1. A composition comprising:
a core material having a taste value;
a polymeric coating substantially surrounding the core material, the polymeric coating comprising a coacervated polymer material comprising a cationic polymer, the cationic polymer comprising gelatin, and an anionic polymer mixture, the anionic polymer mixture comprising a long chain polyphosphate in combination with a medium chain polyphosphate, wherein the ratio of the cationic polymer to the anionic polymer mixture ranges from 8:1 to 11:1 and the polymeric coating has a thickness selected from between 1 μm to 20 μm, wherein the thickness of the polymeric coating is uniform and varies over a range from 0.2 μm to 2.0 μm;
wherein the composition provides a controlled release of a portion of the core material which is taste masked over a time period ranging from 0.5 minute to 2 minutes in the oral cavity and provides release of the remaining core material in a gastrointestinal tract.
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