	US 11,723,871 B2
	Poly(meth)acrylic acid popcorn polymerizates as disintegrants for tablets
Theo Smit, Ludwigshafen (DE); Matthias Karl, Ludwigshafen (DE); Felicitas Guth, Ludwigshafen (DE); Maximilian Angel, Kasendorf (DE); Karl Kolter, Ludwigshafen (DE); Frank Schmidt, Ludwigshafen (DE); and Maximilian Blochberger-Claus, Ludwigshafen (DE)
Assigned to BASF SE, Ludwigshafen (DE)
Appl. No. 17/52,934
Filed by BASF SE, Ludwigshafen (DE)
PCT Filed May 15, 2019, PCT No. PCT/EP2019/062407 § 371(c)(1), (2) Date Nov. 4, 2020, PCT Pub. No. WO2019/219717, PCT Pub. Date Nov. 21, 2019.
Claims priority of application No. 18172745 (EP), filed on May 16, 2018.
Prior Publication US 2021/0251905 A1, Aug. 19, 2021
Int. Cl. A61K 9/20 (2006.01)

CPC A61K 9/2027 (2013.01) [A61K 9/2031 (2013.01)]

16 Claims

1. A solid pharmaceutical dosage form comprising a disintegrant, wherein the disintegrant is a powder-form water-insoluble, low-swelling crosslinked polyacrylate, and wherein the polyacrylate is a popcorn polymer and has a gel time of greater than 30 seconds.