US 10,376,710 B2
Apparatus and method for influencing a condition in a subject
Marc Hebert, Quebec (CA); and Louis Lafleur, Quebec (CA)
Assigned to UNIVERSITÉ LAVAL, Quebec (CA)
Filed by UNIVERSITE LAVAL, Quebec (CA)
Filed on Mar. 8, 2017, as Appl. No. 15/452,985.
Application 15/452,985 is a continuation of application No. 12/733,259, previously published as PCT/CA2008/001491, filed on Aug. 20, 2008.
Claims priority of provisional application 60/935,584, filed on Aug. 20, 2007.
Prior Publication US 2017/0173361 A1, Jun. 22, 2017
Int. Cl. A61N 5/06 (2006.01); A61M 21/00 (2006.01)
CPC A61N 5/0618 (2013.01) [A61M 21/00 (2013.01); A61M 2021/0044 (2013.01); A61M 2021/0083 (2013.01); A61M 2209/088 (2013.01); A61N 2005/0626 (2013.01); A61N 2005/0642 (2013.01); A61N 2005/0648 (2013.01); A61N 2005/0652 (2013.01); A61N 2005/0662 (2013.01)] 27 Claims
OG exemplary drawing
1. A method for stimulating the activity of the suprachiasmatic nuclei in a subject, the method comprising:
providing a first light-emitting source apt to generate a first light having optical parameters known to stimulate an increase in the activity of the suprachiasmatic nuclei of the subject upon eye exposure in continuous emission conditions, said optical parameters including a first spectrum comprised between 420 nm and 540 nm;
generating the first light using said first light-emitting source in a pulsed regime at a pulsing frequency within a frequency range of about 60 Hz to about 70 Hz; and
exposing the eyes of the subject to the generated pulsed first light;
wherein said frequency range is selected such that:
a perception of a stroboscopic effect within said first light by the subject upon said exposing is substantially avoided; and
the stimulation of an increase in the activity of the suprachiasmatic nuclei in the subject resulting from said exposing is about twice as effective as under said continuous emission conditions.