US 10,376,678 B2
Systems and methods for controlling reperfusion in a vessel
Marc-Alan Levine, Pottstown, PA (US)
Assigned to Makaha Medical, LLC., Pottstown, PA (US)
Filed by Makaha Medical, LLC., Pottstown, PA (US)
Filed on Dec. 30, 2016, as Appl. No. 15/395,010.
Claims priority of provisional application 62/276,702, filed on Jan. 8, 2016.
Prior Publication US 2017/0197064 A1, Jul. 13, 2017
Int. Cl. A61M 25/10 (2013.01); A61F 7/12 (2006.01); A61B 17/22 (2006.01); A61M 25/00 (2006.01); A61M 25/09 (2006.01); A61M 39/10 (2006.01); A61M 39/06 (2006.01); A61B 5/1455 (2006.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61M 1/36 (2006.01); A61F 7/00 (2006.01); A61B 17/221 (2006.01); A61B 5/1459 (2006.01); A61B 5/1486 (2006.01); A61B 17/00 (2006.01); A61B 18/02 (2006.01)
CPC A61M 25/10 (2013.01) [A61B 5/14503 (2013.01); A61B 5/14539 (2013.01); A61B 5/14552 (2013.01); A61B 5/14553 (2013.01); A61B 5/4836 (2013.01); A61B 5/6851 (2013.01); A61B 5/6852 (2013.01); A61B 17/22 (2013.01); A61F 7/12 (2013.01); A61M 1/3613 (2014.02); A61M 25/0021 (2013.01); A61M 25/09 (2013.01); A61M 25/104 (2013.01); A61M 39/06 (2013.01); A61M 39/10 (2013.01); A61B 5/1459 (2013.01); A61B 5/14865 (2013.01); A61B 17/221 (2013.01); A61B 2017/00035 (2013.01); A61B 2017/00106 (2013.01); A61B 2017/22067 (2013.01); A61B 2017/22094 (2013.01); A61B 2018/0212 (2013.01); A61B 2562/221 (2013.01); A61F 2007/0056 (2013.01); A61F 2007/126 (2013.01); A61M 2025/0042 (2013.01); A61M 2025/1052 (2013.01); A61M 2205/3375 (2013.01); A61M 2205/3606 (2013.01); A61M 2230/005 (2013.01); A61M 2230/205 (2013.01); A61M 2230/208 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system for controlling reperfusion in a blood vessel of a patient comprising:
a flexible elongated member configured and dimensioned for insertion in the vessel of the patient, the elongated member having a proximal portion and a distal portion, the elongated member configured for insertion so the distal portion extends distal of a blood clot in the blood vessel;
a sensor positioned at the distal portion of the elongated member for positioning distal of the blood clot, the sensor measuring a parameter of blood downstream of the blood clot;
an indicator communicating with the sensor, the indicator indicating a measured parameter of the blood to determine a) a blood clot treatment and b) whether restoration of normal blood flow as a result of clot removal is acceptable or needs to be controlled by a blood flow regulating catheter inserted over the flexible elongated member; and
the blood flow regulating catheter positionable over the flexible elongated member, the catheter having a mechanical thrombectomy device for mechanically removing the blood clot and a balloon distal of the mechanical thrombectomy device, the balloon inflatable to reduce blood flow in the vessel until the parameter of blood rises to an acceptable level, the balloon being partially deflatable to gradually restore blood flow around an outer wall of the balloon and downstream of the balloon and through the vessel as the blood clot is removed.