US 10,376,662 B2
Dry powder inhalers
Peter D. Hodson, Bracknell (GB); Stephen W. Stein, Saint Paul, MN (US); Herbert C. Chiou, Saint Paul, MN (US); Zhaolin Wang, Nanjing (CN); Thomas S. Robison, Saint Paul, MN (US); Michael K. Domroese, Saint Paul, MN (US); and Blake D. Walburg, Minneapolis, MN (US)
Assigned to Adamis Pharmaceuticals Corporation, San Diego, CA (US)
Filed by Adamis Pharmaceuticals Corporation, San Diego, CA (US)
Filed on Sep. 26, 2016, as Appl. No. 15/276,521.
Application 15/276,521 is a continuation of application No. 14/622,617, filed on Feb. 13, 2015, granted, now 9,474,870.
Application 14/622,617 is a continuation of application No. 13/320,762, granted, now 8,985,102, previously published as PCT/US2010/035280, filed on May 18, 2010.
Claims priority of provisional application 61/179,220, filed on May 18, 2009.
Prior Publication US 2017/0080169 A1, Mar. 23, 2017
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 15/00 (2006.01)
CPC A61M 15/0051 (2014.02) [A61M 15/0005 (2014.02); A61M 15/0008 (2014.02); A61M 15/0021 (2014.02); A61M 15/0025 (2014.02); A61M 15/0026 (2014.02); A61M 15/0043 (2014.02); A61M 15/0045 (2013.01); A61M 15/0055 (2014.02); A61M 15/0065 (2013.01); A61M 15/0091 (2013.01); A61M 15/0096 (2014.02); A61M 2202/064 (2013.01); A61M 2205/0216 (2013.01); A61M 2205/0238 (2013.01); A61M 2205/19 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A dry powder inhalation device comprising:
a chamber;
a patient port in communication with the chamber;
an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, wherein the elongate carrier does not comprise a lid component, said powder being releasably retained on a surface of the carrier; an advancement mechanism for advancing a portion of the carrier to within the chamber so that the powder associated with an advanced area of the carrier can be released from the carrier for inhalation by the patient through the patient port; and
a first clamping system and a second clamping system, wherein the first and second clamping systems are configured and arranged such that they are moved into a clamping configuration at least prior to release of the powder associated with the area of the carrier, so that the area of the carrier will be clamped between the first and the second clamping systems during release of the powder associated with the area of the carrier, and wherein at least one of the first and second clamping systems comprises a seal.