US 10,376,660 B2
Dry powder inhalation device
Eric Carl Richardson, Cave Creek, AZ (US)
Assigned to Concentrx Pharmaceuticals, Inc., Durham, NC (US)
Filed by Concentrx Pharmaceuticals, Inc., Durham, NC (US)
Filed on Sep. 14, 2016, as Appl. No. 15/265,428.
Application 15/265,428 is a continuation of application No. 14/343,498, granted, now 9,446,209, previously published as PCT/US2012/054325, filed on Sep. 7, 2012.
Claims priority of provisional application 61/573,496, filed on Sep. 7, 2011.
Prior Publication US 2017/0000960 A1, Jan. 5, 2017
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 15/00 (2006.01)
CPC A61M 15/0008 (2014.02) [A61M 15/002 (2014.02); A61M 15/0021 (2014.02); A61M 15/0028 (2013.01); A61M 15/0043 (2014.02); A61M 15/0091 (2013.01); A61M 2202/064 (2013.01); A61M 2206/16 (2013.01); A61M 2207/00 (2013.01); A61M 2207/10 (2013.01); A61M 2209/06 (2013.01)] 18 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
a body having an upper portion and a lower portion, the body defining a disaggregation chamber, a bottom portion of the disaggregation chamber being within the lower portion and containing a dry powder drug, the lower portion including a raised section extending from an inner surface of the disaggregation chamber, the raised section configured to guide a flow of the dry powder drug within the disaggregation chamber;
a removable partition disposed between the upper portion and the lower portion, the partition retaining the dry powder drug within the bottom portion of the disaggregation chamber when the upper portion and lower portion are coupled together;
an air intake passage configured to place an external volume in fluid communication with the disaggregation chamber when the partition is removed; and
an exit passageway configured to place the external volume in fluid communication with the disaggregation chamber when the partition is removed such that upon inhalation by a patient on the exit passageway, air is drawn from the air intake passage to the disaggregation chamber and on to the exit passageway to disaggregate the dry powder drug within the disaggregation chamber and convey the dry powder drug via the exit passageway to the patient.
 
10. A method of using an inhalation device to deliver a single dose of a pre-metered dry powder drug, comprising:
removing the inhalation device from within a protective overwrap packaging, the inhalation device including a body having an upper portion and a lower portion, the lower portion of the body defining a chamber, the body defining an intake channel and an exit channel, the exit channel fluidically coupled to the chamber via an exit opening at a first end portion of the body, the intake channel fluidically coupled to the chamber via an intake opening at a second end portion of the body;
removing a partition of the inhalation device by pulling an end of the partition, the partition disposed between the upper portion of the inhalation device and the lower portion of the inhalation device to retain the dry powder drug within the chamber before the removing, the end of the partition extending beyond the first end portion of the body of the inhalation device and obstructing a mouthpiece before the removing;
placing, after the removing the partition, a portion of the mouthpiece where air exits the exit channel in a mouth of a patient; and
inhaling on the mouthpiece such that intake air is drawn through the intake channel to produce a flow of intake air within the chamber to disaggregate the dry powder drug, the disaggregated dry powder drug exiting the inhalation device via the exit channel.