US 10,376,615 B2
Micro-needle and micro-needle patch
Jeong Gyu Lee, Daejeon (KR); and Chang Hyeon Kim, Chungcheongnam-do (KR)
Assigned to SMALL LAB Co., Ltd, Daejeon (KR)
Filed by SMALL LAB Co., Ltd, Daejeon (KR)
Filed on Nov. 10, 2015, as Appl. No. 14/936,825.
Claims priority of application No. 10-2014-0155266 (KR), filed on Nov. 10, 2014.
Prior Publication US 2016/0129164 A1, May 12, 2016
Int. Cl. A61L 31/14 (2006.01); A61K 9/00 (2006.01); A61M 37/00 (2006.01); A61L 31/12 (2006.01); A61L 31/16 (2006.01); A61Q 19/08 (2006.01); A61K 8/02 (2006.01); A61K 9/14 (2006.01); A61K 9/70 (2006.01)
CPC A61L 31/146 (2013.01) [A61K 8/0279 (2013.01); A61K 9/0021 (2013.01); A61L 31/129 (2013.01); A61L 31/16 (2013.01); A61M 37/0015 (2013.01); A61Q 19/08 (2013.01); A61K 9/146 (2013.01); A61K 9/7023 (2013.01); A61K 2800/87 (2013.01); A61K 2800/91 (2013.01); A61L 2420/02 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A micro-needle comprising:
a biocompatible matrix having a micro-needle-like shape and having a first material configured to be swollen or dissolved in a living tissue; and
particles provided at at least a portion of a surface or an interior of the biocompatible matrix,
wherein the particles have a particle body and a plurality of pores formed therein,
wherein the particle body comprises a second material different from the first material,
wherein the particles function as drug carriers containing pharmaceutically, medically, or cosmetically effective substance for delivering the pharmaceutically, medically, or cosmetically effective substance to the living tissue,
wherein the effective substance is trapped in the plurality of pores of the particles,
wherein the plurality of pores of the particles comprise open or closed pores, and at least one of porosity, size and opening of the open or closed pores is controlled to control a speed of releasing the effective substance in the living tissue,
wherein the porosity of the particles has a range from 5% to 90%.