US 10,376,614 B2
Medical device and method for producing the same
Hiromasa Kohama, Kanagawa (JP); and Ayako Tokue, Miyagi (JP)
Assigned to TERUMO KABUSHIKI KAISHA, Shibuya-Ku, Tokyo (JP)
Filed by TERUMO KABUSHIKI KAISHA, Shibuya-ku, Tokyo (JP)
Filed on Mar. 2, 2016, as Appl. No. 15/58,294.
Application 15/058,294 is a continuation of application No. PCT/JP2014/069186, filed on Jul. 18, 2014.
Claims priority of application No. 2013-181442 (JP), filed on Sep. 2, 2013; and application No. 2014-013431 (JP), filed on Jan. 28, 2014.
Prior Publication US 2016/0175492 A1, Jun. 23, 2016
Int. Cl. A61L 31/10 (2006.01); A61L 31/14 (2006.01); A61L 29/14 (2006.01); A61L 29/08 (2006.01); A61L 31/04 (2006.01)
CPC A61L 31/10 (2013.01) [A61L 29/085 (2013.01); A61L 29/14 (2013.01); A61L 31/048 (2013.01); A61L 31/14 (2013.01); A61L 2400/10 (2013.01); A61L 2400/18 (2013.01)] 20 Claims
 
1. A medical device capable of being inserted into a living body, the medical device comprising:
a resin coating layer that includes a maleic acid polymer substance,
wherein the resin coating layer is provided on a surface of a base member of the medical device,
wherein the resin coating layer is formed by covalently bonding the maleic acid polymer substance to a reactive functional group which exists on at least the surface of the base member of the medical device, and
wherein the maleic acid polymer substance has a ratio of a peak height of carboxylate with respect to a total peak height of carboxylic acid ester and a carboxylic acid in a range from 1.2 to 1.7 when being measured through infrared spectroscopy, and wherein the ratio of a peak height of carboxylate with respect to a total peak height of carboxylic acid ester and a carboxylic acid in the range from 1.2 to 1.7 when being measured through infrared spectroscopy is obtained by subjecting the maleic acid polymer substance to an alkali treatment,
wherein the maleic acid polymer substance includes a constituting unit of formula (a′), a constituting unit of formula (a″), or a combination thereof:

OG Complex Work Unit Drawing
wherein in formulas (a′) and (a″), X represents an alkali metal or an alkaline earth metal, and R represents a straight chain or branched alkyl group of carbon atom numbers 1 to 24.