US 10,376,610 B2
Regenerated oxidized celulose based hemostatic materialcontaining antifibrolytic agents
Mevlut Ertan, Ankara (TR)
Assigned to Mevlut Ertan, Ankara (TR)
Appl. No. 15/568,488
Filed by Mevlut Ertan, Ankara (TR)
PCT Filed Apr. 21, 2015, PCT No. PCT/TR2015/000166
§ 371(c)(1), (2) Date Oct. 23, 2017,
PCT Pub. No. WO2016/171633, PCT Pub. Date Oct. 27, 2016.
Prior Publication US 2018/0296723 A1, Oct. 18, 2018
Int. Cl. A61L 26/00 (2006.01); A61L 15/28 (2006.01); A61L 15/42 (2006.01); A61L 15/44 (2006.01); A61K 31/197 (2006.01); A61K 31/496 (2006.01); A61K 31/65 (2006.01); A61K 33/245 (2019.01)
CPC A61L 26/0023 (2013.01) [A61K 31/197 (2013.01); A61K 31/496 (2013.01); A61K 31/65 (2013.01); A61K 33/245 (2013.01); A61L 15/28 (2013.01); A61L 15/42 (2013.01); A61L 15/44 (2013.01); A61L 26/008 (2013.01); A61L 26/0061 (2013.01); A61L 26/0066 (2013.01); A61L 2300/21 (2013.01); A61L 2300/214 (2013.01); A61L 2300/216 (2013.01); A61L 2300/404 (2013.01); A61L 2300/406 (2013.01); A61L 2300/418 (2013.01); A61L 2400/04 (2013.01)] 25 Claims
 
1. A hemostatic powder, comprising
18.6-20.2 weight % —COOH on the basis of the total weight of the hemostatic powder,
0.2-0.4 weight % aldehyde, and
0.1-0.25 weight % nitrogen containing regenerated oxidized cellulose powder impregnated with antifibrinolytic tranexamic acid and 6-aminocaproic acid,
wherein the hemostatic powder further comprises an antimicrobial bismuth complex, and 0-1.1 weight % Na+1 ion.