US 10,376,586 B2
Method and compositions for solubilizing non-polar constituents
Michael V. Zumpano, Fairfield, CA (US)
Filed by Entourage Bioscience, LLC, Fairfield, CA (US)
Filed on Feb. 15, 2017, as Appl. No. 15/433,649.
Claims priority of provisional application 62/295,510, filed on Feb. 16, 2016.
Prior Publication US 2017/0232105 A1, Aug. 17, 2017
Int. Cl. A61K 31/05 (2006.01); A61K 47/14 (2017.01); A61K 9/00 (2006.01); C07D 475/02 (2006.01); C07D 239/42 (2006.01); A24B 15/16 (2006.01); A61M 15/00 (2006.01)
CPC A61K 47/14 (2013.01) [A24B 15/167 (2016.11); A61K 9/007 (2013.01); A61K 31/05 (2013.01); C07D 239/42 (2013.01); C07D 475/02 (2013.01); A61M 15/00 (2013.01)] 17 Claims
 
1. A method for solubilizing cannabidiol, the method comprising:
admixing cannabidiol and a medium chain triglyceride carrier liquid comprised of at least one of 0-6.0% of the triglyceride form of hexanoic acid, 6.0-60% of the triglyceride form of octanic acid, and 6.0-60% of the triglyceride form of decanoic acid to form an azeotropic solution;
adding an amount of buffer to the carrier liquid; and
heating the azeotropic solution in a heated vaporization delivery system to vaporize the azeotropic solution.