US 10,376,546 B2
Micronized placental tissue compositions and methods of making and using the same
Brenda S. Morse, Chamblee, GA (US); Somaly Sith, Stone Mountain, GA (US); Randall Spencer, Kennesaw, GA (US); Steven Ray, Kingston, GA (US); John Daniel, Kennesaw, GA (US); and Robert Tofe, Denver, CO (US)
Assigned to MiMedx Group, Inc., Marietta, GA (US)
Filed by MiMedx Group, Inc., Marietta, GA (US)
Filed on May 23, 2014, as Appl. No. 14/286,638.
Application 14/286,638 is a continuation of application No. 13/787,612, filed on Mar. 6, 2013.
Application 13/787,612 is a continuation of application No. PCT/US2012/024798, filed on Feb. 13, 2012.
Claims priority of provisional application 61/442,346, filed on Feb. 14, 2011.
Claims priority of provisional application 61/543,995, filed on Oct. 6, 2011.
Prior Publication US 2014/0255508 A1, Sep. 11, 2014
Int. Cl. A61K 35/50 (2015.01); A61K 35/12 (2015.01); A61K 8/98 (2006.01); A61L 27/36 (2006.01); A61Q 19/00 (2006.01); A61P 17/02 (2006.01)
CPC A61K 35/50 (2013.01) [A61K 8/982 (2013.01); A61K 35/12 (2013.01); A61L 27/3604 (2013.01); A61L 27/3683 (2013.01); A61L 27/3695 (2013.01); A61P 17/02 (2018.01); A61Q 19/00 (2013.01); A61L 2400/06 (2013.01); A61L 2430/34 (2013.01)] 5 Claims
 
1. A method for promoting wound healing, wherein the method comprises contacting a wound with an injectable composition comprising micronized placental tissue particles, said tissue particles consisting essentially of an amnion layer and a chorion layer, wherein the chorion layer is layered directly over the amnion layer, wherein the intermediate layer has been substantially removed, wherein the epithelial layer of said amnion layer has been substantially removed, wherein the amnion layer has an exposed basement membrane and an exposed fibroblast layer and further wherein the wound healing is associated with an orthopedic application.