US 10,376,541 B2
Topical antibiotic formulations
Perry Antelman, Sharon, MA (US); Bharat Madhavan, Kingston, RI (US); and Shalom Lampert, Maalot (IL)
Assigned to AIDANCE SKINCARE & TOPICAL SOLUTIONS LLC, Woonsocket, RI (US)
Filed by AIDANCE SKINCARE & TOPICAL SOLUTIONS LLC, Woonsocket, RI (US)
Filed on Feb. 26, 2018, as Appl. No. 15/905,797.
Application 15/905,797 is a continuation in part of application No. 15/064,623, filed on Mar. 9, 2016, granted, now 9,901,541.
Application 15/064,623 is a continuation of application No. PCT/IB2015/050630, filed on Jan. 27, 2015.
Claims priority of provisional application 61/931,944, filed on Jan. 27, 2014.
Prior Publication US 2018/0185412 A1, Jul. 5, 2018
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 33/38 (2006.01); A61P 31/00 (2006.01); C07C 51/41 (2006.01)
CPC A61K 33/38 (2013.01) [A61P 31/00 (2018.01); C07C 51/412 (2013.01); C07C 51/418 (2013.01)] 20 Claims
 
1. A method of producing a silver(II) carboxylate from a silver(II) oxide, the method comprising:
(a) mixing a carboxylic acid and the silver(II) oxide to produce a reaction mixture; and
(b) heating the reaction mixture to produce a first formulation containing an aliphatic silver carboxylate, the silver of the aliphatic silver carboxylate having a nominal valence of 2.