US 10,376,540 B2
Tungsten (VI) salts used to treat infertility, for stimulating fertility and normal reproduction in a non-diabetic female mammal, and for improving the effectiveness of assisted reproduction techniques
Ignacio Canals Almazán, Sant Quirze del Vallés (ES); and Agnès Arbat Bugié, Sant Quirze del Vallés (ES)
Assigned to OXOLIKE, S.L., Sant Quirze del Vallés (ES)
Appl. No. 15/327,292
Filed by OXOLIFE, S.L., Sant Quirze del Vallés (ES)
PCT Filed Jul. 21, 2014, PCT No. PCT/ES2014/070586
§ 371(c)(1), (2) Date Jan. 18, 2017,
PCT Pub. No. WO2016/012632, PCT Pub. Date Jan. 28, 2016.
Prior Publication US 2017/0173074 A1, Jun. 22, 2017
Int. Cl. A23L 2/52 (2006.01); A61K 9/20 (2006.01); A61K 9/28 (2006.01); A61K 9/48 (2006.01); A23L 33/16 (2016.01); A61K 33/24 (2019.01); A61K 33/30 (2006.01); A61P 15/08 (2006.01); C01G 41/00 (2006.01); C01G 41/02 (2006.01)
CPC A61K 33/24 (2013.01) [A23L 2/52 (2013.01); A23L 33/16 (2016.08); A61K 9/20 (2013.01); A61K 9/28 (2013.01); A61K 9/48 (2013.01); A61K 33/30 (2013.01); A61P 15/08 (2018.01); C01G 41/00 (2013.01); C01G 41/02 (2013.01); A23V 2002/00 (2013.01)] 18 Claims
 
1. A method for favoring normal reproduction and fertility or for increasing efficacy of an assisted reproductive technique in a non-diabetic female mammal, said method comprising administering to said mammal tungsten (VI) salt, or a solvate thereof;
wherein said salt is administered at a daily dose of between 0.001 mg and 1000 mg of the tungsten (VI) salt per kg of body weight of the mammal;
wherein said mammal is not infertile,
wherein the normal reproduction and fertility is a state of fertility in which pregnancy is achieved in a period of 12 months of regular, unprotected sexual intercourse; and
wherein the assisted reproductive technique is selected from a technique comprising induction of ovulation, artificial insemination or in vitro fertilization;
such that the normal reproduction and fertility in said mammal is favored or the efficacy of said assisted reproductive technique in said mammal is increased.