US 10,376,528 B2
Composition comprising ketone body and nicotinamide adenine dinucleotide modulator and methyl donor
Michael A. Schmidt, Fort Collins, CO (US)
Assigned to TECTON GROUP, LLC, Memphis, TN (US)
Filed by Tecton Group, LLC, Memphis, TN (US)
Filed on Mar. 10, 2017, as Appl. No. 15/456,407.
Prior Publication US 2018/0256612 A1, Sep. 13, 2018
Int. Cl. A61K 31/683 (2006.01); A61K 45/06 (2006.01); A61K 31/22 (2006.01); A61K 31/19 (2006.01); A61K 31/6615 (2006.01)
CPC A61K 31/683 (2013.01) [A61K 31/19 (2013.01); A61K 31/22 (2013.01); A61K 31/6615 (2013.01); A61K 45/06 (2013.01)] 12 Claims
1. A composition comprising a therapeutically effective amount of: (i) an exogenous ketone body comprising 3-hydroxybutyrate (“BHB”) or an ester of BHB, (ii) exogenous nicotinamide adenine dinucleotide (“NAD”) modulator, and (iii) a methyl donor, wherein the composition is in a single unit form, and wherein said NAD modulator is present in an amount from 125 mg to 2000 mg, and the ratio (w/w) of the exogenous ketone body to the NAD modulator is from 160:1 to 10:1.