US 10,376,527 B2
Oral composition of celecoxib for treatment of pain
Ankit Baheti, Indore (IN); Bijay Kumar Padhi, Buguda (IN); Supritha Vakada, Hyderabad (IN); and Rajeev Singh Raghuvanshi, Gurgaon (IN)
Assigned to DR. REDDY'S LABORATORIES LTD., Hyderabad (IN)
Filed by Dr. Reddy's Laboratories Ltd., Hyderabad, Telangana (IN)
Filed on Mar. 15, 2018, as Appl. No. 15/922,170.
Application 15/922,170 is a continuation of application No. 15/712,415, filed on Sep. 22, 2017, granted, now 9,949,990.
Application 15/712,415 is a continuation of application No. 15/374,951, filed on Dec. 9, 2016, granted, now 9,795,620, issued on Oct. 24, 2017.
Application 15/374,951 is a continuation of application No. 15/167,922, filed on May 27, 2016, granted, now 9,572,819, issued on Feb. 21, 2017.
Claims priority of application No. 2682/CHE/2015 (IN), filed on May 28, 2015; and application No. 6614/CHE/2015 (IN), filed on Dec. 10, 2015.
Prior Publication US 2018/0200270 A1, Jul. 19, 2018
Int. Cl. A61K 31/635 (2006.01); A61K 47/14 (2017.01); A61K 47/44 (2017.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/10 (2017.01); A61K 9/10 (2006.01); A61K 31/415 (2006.01); A61K 47/26 (2006.01); C07D 231/12 (2006.01)
CPC A61K 31/635 (2013.01) [A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 31/415 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/26 (2013.01); A61K 47/44 (2013.01); C07D 231/12 (2013.01)] 30 Claims
 
1. A method of rendering a human subject pain free within 2 hours, wherein said method comprising administering to said subject a stable oral pharmaceutical composition comprising a reduced dose of celecoxib relative to conventional celecoxib in 400 mg oral capsules, a solubilizer, a medium chain glyceride, a polar solvent, and a pharmaceutically-acceptable excipient g.