US 10,376,514 B2
Therapeutic thiophene-, furan-, and pyridine-fused azolopyrimidin-5-(6H)-ones
Bryan Branstetter, Carlsbad, CA (US); James Breitenbucher, Escondido, CA (US); Brian Dyck, San Diego, CA (US); Laurent Gomez, San Diego, CA (US); Andrew Richard Hudson, San Diego, CA (US); Tami Jo Marrone, Carlsbad, CA (US); Marco Peters, San Diego, CA (US); Troy Vickers, San Diego, CA (US); and Michael I. Weinhouse, Escondido, CA (US)
Assigned to Dart Neuroscience (Cayman) Ltd., Grand Cayman (KY)
Filed by Dart Neuroscience (Cayman) Ltd., Grand Cayman (KY)
Filed on Oct. 18, 2018, as Appl. No. 16/164,726.
Application 14/853,856 is a division of application No. 13/920,974, filed on Jun. 18, 2013, granted, now 9,175,010, issued on Nov. 3, 2015.
Application 16/164,726 is a continuation of application No. 15/394,058, filed on Dec. 29, 2016, granted, now 10,105,367.
Application 15/394,058 is a continuation of application No. 14/853,856, filed on Sep. 14, 2015, granted, now 9,533,996, issued on Jan. 3, 2017.
Claims priority of provisional application 61/661,091, filed on Jun. 18, 2012.
Prior Publication US 2019/0046535 A1, Feb. 14, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. C07D 495/14 (2006.01); C07D 495/22 (2006.01); C07D 471/14 (2006.01); C07D 471/22 (2006.01); C07D 487/14 (2006.01); C07D 487/22 (2006.01); C07D 491/22 (2006.01); A61K 31/519 (2006.01); C07D 498/08 (2006.01); C07D 491/147 (2006.01); C07D 491/107 (2006.01); C07D 519/00 (2006.01); C07D 495/12 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/553 (2006.01); A61K 31/5386 (2006.01); A61P 25/00 (2006.01); A61P 9/00 (2006.01)
CPC A61K 31/519 (2013.01) [A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 31/541 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/553 (2013.01); A61P 9/00 (2018.01); A61P 25/00 (2018.01); C07D 471/14 (2013.01); C07D 487/14 (2013.01); C07D 491/107 (2013.01); C07D 491/147 (2013.01); C07D 491/22 (2013.01); C07D 495/12 (2013.01); C07D 495/14 (2013.01); C07D 495/22 (2013.01); C07D 498/08 (2013.01); C07D 519/00 (2013.01)] 20 Claims
 
1. A compound, or a pharmaceutically acceptable salt thereof, having the structure:

OG Complex Work Unit Drawing

OG Complex Work Unit Drawing

OG Complex Work Unit Drawing