US 10,376,507 B2
Method of treating a patient with a CYP3A4 substrate drug
Sundar Srinivasan, Corona Del Mar, CA (US); and Christina Chow, Seattle, WA (US)
Assigned to BOW RIVER LLC, Corona del Mar, CA (US)
Filed by Bow River LLC, Corona Del Mar, CA (US)
Filed on May 16, 2017, as Appl. No. 15/596,585.
Prior Publication US 2018/0333409 A1, Nov. 22, 2018
Int. Cl. A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/495 (2006.01)
CPC A61K 31/496 (2013.01) [A61K 31/495 (2013.01); A61K 31/4985 (2013.01)] 17 Claims
1. A method of treating a patient for a condition selected from schizophrenia or bipolar depression with lurasidone, wherein the patient is treated with posaconazole, comprising:
(a) stopping posaconazole treatment;
(b) delaying administering a first dose of lurasidone ranging from 20 mg to 120 mg until
at least 9 days after stopping posaconazole in step (a).