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US 10,376,481 B2 |
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Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
Noah Bell, Berkeley, CA (US); Christopher Carreras, Belmont, CA (US); Michael Robert Leadbetter, San Leandro, CA (US); Jason Gustaf Lewis, Castro Valley, CA (US); Jeffrey W. Jacobs, San Mateo, CA (US); Irina Dotsenko, San Jose, CA (US); Dean Dragoli, Los Altos, CA (US); Ying He, Pleasanton, CA (US); Andrew King, Dublin, CA (US); and Matthew Siegel, Menlo Park, CA (US) |
Assigned to ARDELYX, INC., Fremont, CA (US) |
Filed by ARDELYX, INC, Fremont, CA (US) |
Filed on Jan. 9, 2017, as Appl. No. 15/402,213. |
Application 15/402,213 is a continuation in part of application No. 14/421,451, abandoned, previously published as PCT/GB2013/052192, filed on Aug. 20, 2013. |
Claims priority of provisional application 61/691,635, filed on Aug. 21, 2012. |
Prior Publication US 2017/0368004 A1, Dec. 28, 2017 |
Int. Cl. A61K 31/17 (2006.01); A61K 31/4545 (2006.01); A61K 31/25 (2006.01); A61K 31/18 (2006.01); A61K 31/167 (2006.01); A61K 31/03 (2006.01); A61K 31/10 (2006.01); A61K 31/015 (2006.01); A61K 31/40 (2006.01); A61K 31/4453 (2006.01) |