US 10,376,468 B2
Block copolymers and self-assembling nanoparticles formed therefrom
Dylan Boday, Tucson, AZ (US); Willy Chin, Singapore (SG); Mareva B. Fevre, San Jose, CA (US); Jeannette Garcia, San Leandro, CA (US); James L. Hedrick, Pleasanton, CA (US); Eunice Leong, Singapore (SG); Nathaniel H. Park, San Jose, CA (US); Rudy J. Wojtecki, San Jose, CA (US); and Yi Yan Yang, Singapore (SG)
Assigned to International Business Machines Corporation, Armonk, NY (US); and Institute of Bioengineering and Nanotechnology, Biomedical Sciences Institute, Matrix (SG)
Filed by International Business Machines Corporation, Armonk, NY (US)
Filed on Dec. 5, 2017, as Appl. No. 15/832,157.
Prior Publication US 2019/0167584 A1, Jun. 6, 2019
Int. Cl. A61K 38/00 (2006.01); A61P 43/00 (2006.01); A61K 47/00 (2006.01); A61K 9/107 (2006.01); A61K 47/69 (2017.01); A61K 47/60 (2017.01); C08G 64/02 (2006.01); C08G 81/00 (2006.01); C08G 64/18 (2006.01); A61K 31/351 (2006.01); A61K 31/12 (2006.01)
CPC A61K 9/1075 (2013.01) [A61K 47/60 (2017.08); A61K 47/6907 (2017.08); C08G 64/025 (2013.01); C08G 64/183 (2013.01); C08G 81/00 (2013.01); A61K 31/12 (2013.01); A61K 31/351 (2013.01)] 18 Claims
 
1. A block copolymer comprising:
a hydrophilic block; and
a hydrophobic block containing at least one thioether functional group, the block copolymer having the structure of formula I:

OG Complex Work Unit Drawing
wherein m is 114 and x is 5.