US 10,376,363 B2
Replacement mitral valve, delivery system for replacement mitral valve and methods of use
Arshad Quadri, West Hartford, CT (US); J. Brent Ratz, Winchester, MA (US); Yen Liao, Arlington, VA (US); Julio Cesar Sanchez, Garden Grove, CA (US); Alexander H. Cooper, Costa Mesa, CA (US); Glen T. Rabito, Lake Forest, CA (US); Siddharth Vad, Irvine, CA (US); Luca Pesce, Huntington Beach, CA (US); Kevin M. Stewart, Newport Beach, CA (US); and David Robert Landon, Costa Mesa, CA (US)
Assigned to EDWARDS LIFESCIENCES CARDIAQ LLC, Irvine, CA (US)
Filed by Edwards Lifesciences CardiAQ LLC, Irvine, CA (US)
Filed on Apr. 28, 2016, as Appl. No. 15/141,684.
Claims priority of provisional application 62/300,478, filed on Feb. 26, 2016.
Claims priority of provisional application 62/210,165, filed on Aug. 26, 2015.
Claims priority of provisional application 62/163,932, filed on May 19, 2015.
Claims priority of provisional application 62/155,405, filed on Apr. 30, 2015.
Prior Publication US 2016/0317301 A1, Nov. 3, 2016
Int. Cl. A61F 2/24 (2006.01)
CPC A61F 2/2436 (2013.01) [A61F 2/2418 (2013.01); A61F 2/2409 (2013.01); A61F 2230/0065 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A transseptal delivery system for replacement mitral valve implantation, the delivery system comprising:
a nose cone shaft having a proximal end and a distal end and a lumen extending therethrough;
a nose cone provided on the distal end of the nose cone shaft;
an inner retention shaft slideably positioned over the nose cone shaft, the inner retention shaft having a proximal end and a distal end;
an inner retention ring provided on the distal end of the inner retention shaft, the inner retention ring configured to receive struts at a proximal portion of a replacement mitral valve prosthesis;
a mid shaft slideably positioned over the inner retention shaft, the mid shaft having a proximal end and a distal end;
an outer retention ring provided on the distal end of the mid shaft, the outer retention ring configured to be positioned over the inner retention ring to hold the proximal portion of the replacement mitral valve prosthesis within the inner retention ring; and
an outer sheath assembly slideably positioned over the mid shaft and over the outer retention ring, the outer sheath assembly configured to radially restrain a distal portion of the replacement mitral valve prosthesis when the proximal portion of the replacement mitral valve prosthesis is held by the outer retention ring within the inner retention ring;
wherein the mid shaft comprises a longitudinally pre-compressed tube located within the outer sheath assembly, the longitudinally pre-compressed tube having a reduced length of about ⅛, ⅙, ¼, ½, or 1 inches from a natural state, wherein the longitudinally pre-compressed tube is configured to lengthen during bending of the delivery system so that deflection of the mid shaft does not substantially change the location of the outer retention ring relative to the inner retention ring; and
wherein the mid shaft provides a distal force on the outer retention ring.
 
16. The transseptal delivery system of claim 1, wherein the outer retention ring is a separate structural component attached to the mid shaft.