US 10,376,361 B2
Techniques for percutaneous mitral valve replacement and sealing
Yossi Gross, Moshav Mazor (IL); Gil Hacohen, Ramat Gan (IL); Eran Miller, Moshav Beit Elazari (IL); and Yuval Zipory, Modi'in (IL)
Assigned to CARDIOVALVE LTD., Or Yehuda (IL)
Filed by CARDIOVALVE LTD., Or Yehuda (IL)
Filed on Jul. 25, 2018, as Appl. No. 16/45,059.
Application 16/045,059 is a continuation of application No. 15/213,791, filed on Jul. 19, 2016, granted, now 10,245,143.
Application 15/213,791 is a continuation of application No. 14/237,264, abandoned, previously published as PCT/IL2012/000292, filed on Aug. 5, 2012.
Application 14/237,264 is a continuation in part of application No. 13/412,814, filed on Mar. 6, 2012, granted, now 8,852,272.
Claims priority of provisional application 61/588,892, filed on Jan. 20, 2012.
Claims priority of provisional application 61/555,160, filed on Nov. 3, 2011.
Claims priority of provisional application 61/537,276, filed on Sep. 21, 2011.
Claims priority of provisional application 61/525,281, filed on Aug. 19, 2011.
Claims priority of provisional application 61/515,372, filed on Aug. 5, 2011.
Prior Publication US 2018/0344457 A1, Dec. 6, 2018
Int. Cl. A61F 2/24 (2006.01); A61F 2/848 (2013.01)
CPC A61F 2/2418 (2013.01) [A61F 2/2409 (2013.01); A61F 2/2436 (2013.01); A61F 2/2439 (2013.01); A61F 2/2433 (2013.01); A61F 2/2442 (2013.01); A61F 2/848 (2013.01); A61F 2220/0016 (2013.01); A61F 2220/0025 (2013.01); A61F 2220/0091 (2013.01); A61F 2230/005 (2013.01); A61F 2230/0013 (2013.01); A61F 2230/0054 (2013.01); A61F 2230/0078 (2013.01); A61F 2250/006 (2013.01); A61F 2250/0015 (2013.01); A61F 2250/0069 (2013.01); A61F 2250/0071 (2013.01)] 31 Claims
OG exemplary drawing
 
1. Apparatus, for use with a native valve of a heart of a subject, the native valve defining an area, the apparatus comprising:
an annular upstream support portion, comprising an expandable first frame, the upstream support portion configured to be placed against an upstream surface of the native valve;
a flexible polyester connector;
an anchoring element, flexibly coupled to the upstream support portion by the connector, and configured to anchor the upstream support portion to the native valve by engaging tissue of the native valve; and
a prosthetic valve,
wherein:
the upstream support portion is configured to support the prosthetic valve at the native valve, and
the prosthetic valve:
comprises (i) an expandable second frame that defines a lumen therethrough, and (ii) a plurality of prosthetic leaflets disposed within the lumen and coupled to the second frame,
is configured to be positioned inward from the upstream support portion, and
has a cross-sectional area that is less than 90 percent of the area defined by the native valve.