US 10,376,317 B2 | ||
Method and system for image processing and patient-specific modeling of blood flow | ||
Charles A. Taylor, Menlo Park, CA (US) | ||
Assigned to HeartFlow, Inc., Redwood City, CA (US) | ||
Filed by HeartFlow, Inc., Redwood City, CA (US) | ||
Filed on Aug. 25, 2016, as Appl. No. 15/247,231. | ||
Application 13/014,835 is a division of application No. 13/013,561, filed on Jan. 25, 2011, granted, now 8,315,812, issued on Nov. 20, 2012. | ||
Application 15/247,231 is a continuation of application No. 14/866,098, filed on Sep. 25, 2015, granted, now 9,801,689. | ||
Application 14/866,098 is a continuation of application No. 14/276,442, filed on May 13, 2014, granted, now 9,226,672, issued on Jan. 5, 2016. | ||
Application 14/276,442 is a continuation of application No. 13/658,739, filed on Oct. 23, 2012, granted, now 10,179,030. | ||
Application 13/658,739 is a continuation of application No. 13/014,835, filed on Jan. 27, 2011, granted, now 8,311,747, issued on Nov. 13, 2012. | ||
Claims priority of provisional application 61/404,429, filed on Oct. 1, 2010. | ||
Claims priority of provisional application 61/402,345, filed on Aug. 27, 2010. | ||
Claims priority of provisional application 61/402,308, filed on Aug. 26, 2010. | ||
Claims priority of provisional application 61/401,915, filed on Aug. 20, 2010. | ||
Claims priority of provisional application 61/401,462, filed on Aug. 12, 2010. | ||
Prior Publication US 2016/0364860 A1, Dec. 15, 2016 | ||
This patent is subject to a terminal disclaimer. | ||
Int. Cl. A61B 5/00 (2006.01); A61B 5/02 (2006.01); A61B 5/11 (2006.01); A61B 5/22 (2006.01); A61B 6/00 (2006.01); A61B 6/03 (2006.01); A61B 8/02 (2006.01); A61B 8/04 (2006.01); A61B 8/06 (2006.01); A61B 8/08 (2006.01); A61M 5/00 (2006.01); G06G 7/60 (2006.01); G06K 9/00 (2006.01); G06K 9/46 (2006.01); G06K 9/52 (2006.01); G06K 9/62 (2006.01); G06T 7/00 (2017.01); G06T 7/11 (2017.01); G06T 7/12 (2017.01); G06T 7/13 (2017.01); A61B 34/10 (2016.01); G06F 17/10 (2006.01); A61B 34/00 (2016.01); G16B 5/00 (2019.01); G16B 45/00 (2019.01); A61B 5/026 (2006.01); A61B 5/029 (2006.01); G01R 33/563 (2006.01); A61B 5/107 (2006.01); G06T 17/00 (2006.01); A61B 5/021 (2006.01); G06F 17/50 (2006.01); A61B 5/024 (2006.01); G06F 19/00 (2018.01); G06T 7/20 (2017.01); G06T 11/00 (2006.01); G06T 11/20 (2006.01); A61B 5/055 (2006.01); G06T 17/20 (2006.01); G06T 15/10 (2011.01); G06T 11/60 (2006.01); G06T 7/60 (2017.01); G06T 7/70 (2017.01); G06T 7/73 (2017.01); G06T 7/149 (2017.01); G06T 7/62 (2017.01); G01R 33/56 (2006.01); G16H 10/60 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16H 30/20 (2018.01); G16H 30/40 (2018.01); G16H 10/40 (2018.01); G16H 50/70 (2018.01); A61B 90/00 (2016.01) |
CPC A61B 34/10 (2016.02) [A61B 5/004 (2013.01); A61B 5/0035 (2013.01); A61B 5/0044 (2013.01); A61B 5/02 (2013.01); A61B 5/021 (2013.01); A61B 5/024 (2013.01); A61B 5/026 (2013.01); A61B 5/02007 (2013.01); A61B 5/029 (2013.01); A61B 5/02028 (2013.01); A61B 5/0263 (2013.01); A61B 5/055 (2013.01); A61B 5/1075 (2013.01); A61B 5/1118 (2013.01); A61B 5/22 (2013.01); A61B 5/4848 (2013.01); A61B 5/6852 (2013.01); A61B 5/7246 (2013.01); A61B 5/7275 (2013.01); A61B 5/7278 (2013.01); A61B 5/745 (2013.01); A61B 6/03 (2013.01); A61B 6/032 (2013.01); A61B 6/481 (2013.01); A61B 6/503 (2013.01); A61B 6/504 (2013.01); A61B 6/507 (2013.01); A61B 6/5205 (2013.01); A61B 6/5217 (2013.01); A61B 6/5229 (2013.01); A61B 8/02 (2013.01); A61B 8/04 (2013.01); A61B 8/06 (2013.01); A61B 8/065 (2013.01); A61B 8/481 (2013.01); A61B 8/5223 (2013.01); A61B 8/5261 (2013.01); A61B 34/25 (2016.02); A61M 5/007 (2013.01); G01R 33/5601 (2013.01); G01R 33/5635 (2013.01); G01R 33/56366 (2013.01); G06F 17/10 (2013.01); G06F 17/5009 (2013.01); G06F 17/5018 (2013.01); G06F 19/00 (2013.01); G06F 19/321 (2013.01); G06F 19/324 (2013.01); G06G 7/60 (2013.01); G06K 9/00147 (2013.01); G06K 9/46 (2013.01); G06K 9/4604 (2013.01); G06K 9/52 (2013.01); G06K 9/6215 (2013.01); G06K 9/6267 (2013.01); G06K 9/6298 (2013.01); G06T 7/0012 (2013.01); G06T 7/0014 (2013.01); G06T 7/11 (2017.01); G06T 7/12 (2017.01); G06T 7/13 (2017.01); G06T 7/149 (2017.01); G06T 7/20 (2013.01); G06T 7/60 (2013.01); G06T 7/62 (2017.01); G06T 7/70 (2017.01); G06T 7/73 (2017.01); G06T 7/74 (2017.01); G06T 11/00 (2013.01); G06T 11/001 (2013.01); G06T 11/008 (2013.01); G06T 11/20 (2013.01); G06T 11/60 (2013.01); G06T 15/10 (2013.01); G06T 17/00 (2013.01); G06T 17/005 (2013.01); G06T 17/20 (2013.01); G16B 5/00 (2019.02); G16B 45/00 (2019.02); G16H 10/40 (2018.01); G16H 10/60 (2018.01); G16H 30/20 (2018.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); G16H 50/70 (2018.01); A61B 2034/104 (2016.02); A61B 2034/105 (2016.02); A61B 2034/107 (2016.02); A61B 2034/108 (2016.02); A61B 2090/374 (2016.02); A61B 2090/3762 (2016.02); A61B 2090/3764 (2016.02); A61B 2576/00 (2013.01); A61B 2576/023 (2013.01); G06K 2009/4666 (2013.01); G06T 2200/04 (2013.01); G06T 2207/10012 (2013.01); G06T 2207/10072 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/10088 (2013.01); G06T 2207/10104 (2013.01); G06T 2207/10108 (2013.01); G06T 2207/20036 (2013.01); G06T 2207/20124 (2013.01); G06T 2207/30048 (2013.01); G06T 2207/30104 (2013.01); G06T 2210/41 (2013.01); G06T 2211/404 (2013.01); Y02A 90/22 (2018.01); Y02A 90/26 (2018.01)] | 17 Claims |
1. A method for image processing for predicting a post-stenting blood flow characteristic for a coronary artery stenosis from pre-stenting medical image data, comprising: determining a patient-specific anatomical model of a patient's coronary arteries from the pre-stenting medical image data of the patient;
simulating blood flow through at least a portion of the patient-specific anatomical model of the coronary arteries using a pressure-loss model, wherein the pressure-loss model simulates blood flow through at least a portion of the patient-specific anatomical model;
determining a target stenosis region of the patient-specific anatomical model corresponding to a stenosis in the patient's coronary arteries;
determining a change in pressure over the target stenosis region in the patient-specific anatomical model of the coronary arteries based on the simulated blood flow;
simulating the insertion of a stent by widening a coronary artery of the patient-specific anatomical model at the target stenosis region; and
determining at least one predicted post-stenting blood flow characteristic value for the target stenosis region by re-simulating blood flow through the patient-specific anatomical model of the coronary arteries using a pressure-loss model, the at least one predicted post-stenting blood flow characteristic value being used to determine whether to place a stent in the patient.
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