US 10,376,312 B2
Methods and apparatus for monopolar renal neuromodulation
Denise Zarins, Saratoga, CA (US); Hanson Gifford, III, Woodside, CA (US); Mark Deem, Mountain View, CA (US); Howard R. Levin, Teaneck, NJ (US); Mark Gelfand, New York, NY (US); and Nicolas Zadno, Fremont, CA (US)
Assigned to Medtronic Ardian Luxembourg S.a.r.l., Luxembourg (LU)
Filed by Medtronic Ardian Luxembourg S.a.r.l., Luxembourg (LU)
Filed on Oct. 5, 2018, as Appl. No. 16/153,376.
Application 13/371,285 is a division of application No. 11/403,329, filed on Apr. 13, 2006, granted, now 8,131,371, issued on Mar. 6, 2012.
Application 16/153,376 is a continuation of application No. 15/623,428, filed on Jun. 15, 2017, granted, now 10,111,707.
Application 15/623,428 is a continuation of application No. 15/231,517, filed on Aug. 8, 2016, granted, now 9,707,035, issued on Jul. 18, 2017.
Application 15/231,517 is a continuation of application No. 15/075,789, filed on Mar. 21, 2016, granted, now 9,445,867, issued on Sep. 20, 2016.
Application 15/075,789 is a continuation of application No. 14/611,651, filed on Feb. 2, 2015, granted, now 9,327,122, issued on May 3, 2016.
Application 14/611,651 is a continuation of application No. 13/958,450, filed on Aug. 2, 2013, abandoned.
Application 13/958,450 is a continuation of application No. 13/371,285, filed on Feb. 10, 2012, abandoned.
Application 11/403,329 is a continuation in part of application No. 11/129,765, filed on May 13, 2005, granted, now 7,653,438, issued on Jan. 26, 2010.
Application 11/129,765 is a continuation in part of application No. 10/408,665, filed on Apr. 8, 2003, granted, now 7,162,303, issued on Jan. 9, 2007.
Application 10/408,665 is a continuation in part of application No. 11/189,563, filed on Jul. 25, 2005, granted, now 8,145,316, issued on Mar. 27, 2012.
Application 11/189,563 is a continuation in part of application No. 11/266,993, filed on Nov. 4, 2005, granted, now 7,756,583, issued on Jul. 13, 2010.
Application 11/266,993 is a continuation in part of application No. 11/363,867, filed on Feb. 27, 2006, granted, now 7,620,451, issued on Nov. 17, 2009.
Claims priority of provisional application 60/616,254, filed on Oct. 5, 2004.
Claims priority of provisional application 60/624,793, filed on Nov. 2, 2004.
Claims priority of provisional application 60/442,970, filed on Jan. 29, 2003.
Claims priority of provisional application 60/415,575, filed on Oct. 3, 2002.
Claims priority of provisional application 60/370,190, filed on Apr. 8, 2002.
Claims priority of provisional application 60/813,589, filed on Dec. 29, 2005.
Prior Publication US 2019/0090944 A1, Mar. 28, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 18/14 (2006.01); A61N 1/36 (2006.01); A61B 18/16 (2006.01); A61B 18/12 (2006.01); A61N 1/05 (2006.01); A61N 1/32 (2006.01); A61B 18/00 (2006.01); A61B 17/00 (2006.01)
CPC A61B 18/1492 (2013.01) [A61B 18/12 (2013.01); A61B 18/1206 (2013.01); A61B 18/1482 (2013.01); A61B 18/16 (2013.01); A61N 1/05 (2013.01); A61N 1/0551 (2013.01); A61N 1/327 (2013.01); A61N 1/36017 (2013.01); A61N 1/36117 (2013.01); A61N 1/36139 (2013.01); H05K 999/99 (2013.01); A61B 2017/00154 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00059 (2013.01); A61B 2018/00214 (2013.01); A61B 2018/00261 (2013.01); A61B 2018/00267 (2013.01); A61B 2018/00279 (2013.01); A61B 2018/00404 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00511 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 2018/00642 (2013.01); A61B 2018/00648 (2013.01); A61B 2018/00791 (2013.01); A61B 2018/00875 (2013.01); A61B 2018/124 (2013.01); A61B 2018/1253 (2013.01); A61B 2018/1435 (2013.01); A61B 2018/1467 (2013.01); A61B 2018/1472 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method, comprising:
intravascularly positioning a renal denervation catheter in a low-profile delivery arrangement within a renal blood vessel of a hypertensive human patient and adjacent to renal nerves innervating a kidney of the patient;
transforming the catheter from the low-profile delivery arrangement to an expanded arrangement at a treatment site within the renal blood vessel,
wherein, in the expanded arrangement, a plurality of energy delivery elements of the renal denervation catheter are positioned in contact with an inner wall of the renal blood vessel of the patient; and
delivering an electric field between the plurality of energy delivery elements and a ground pad coupled to an exterior of the patient,
wherein delivering the electric field comprises delivering a substantially uniform circumferential energy field about the renal blood vessel at the treatment site, and
wherein delivering the electric field attenuates neural communication along the renal nerves and results in a therapeutically beneficial reduction in blood pressure of the patient.