US 10,376,273 B2
Methods and apparatuses for treatment of meibomian glands
Donald R. Korb, Boston, MA (US); Timothy R. Willis, Raleigh, NC (US); and Stephen M. Grenon, Durham, NC (US)
Assigned to TearScience, Inc., Morrisville, NC (US)
Filed by TearScience, Inc., Morrisville, NC (US)
Filed on Oct. 9, 2014, as Appl. No. 14/510,863.
Application 14/510,863 is a continuation of application No. 13/183,901, filed on Jul. 15, 2011, granted, now 9,216,028.
Application 13/183,901 is a continuation of application No. 11/541,418, filed on Sep. 29, 2006, granted, now 7,981,145, issued on Jul. 19, 2011.
Application 11/541,418 is a continuation in part of application No. 11/434,054, filed on May 15, 2006, granted, now 8,083,787, issued on Dec. 27, 2011.
Application 11/434,054 is a continuation in part of application No. 11/434,033, filed on May 15, 2006, granted, now 8,915,253.
Application 11/434,033 is a continuation in part of application No. 11/434,446, filed on May 15, 2006, abandoned.
Claims priority of provisional application 60/700,233, filed on Jul. 18, 2005.
Prior Publication US 2015/0100063 A1, Apr. 9, 2015
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 7/00 (2006.01); A61F 7/02 (2006.01); A61H 7/00 (2006.01); A61N 7/00 (2006.01); A61B 17/22 (2006.01); A61B 18/04 (2006.01); A61B 18/12 (2006.01); A61F 9/007 (2006.01); A61H 15/00 (2006.01)
CPC A61B 17/22004 (2013.01) [A61F 7/02 (2013.01); A61F 9/00772 (2013.01); A61H 7/00 (2013.01); A61B 18/12 (2013.01); A61B 2018/046 (2013.01); A61B 2018/048 (2013.01); A61F 2007/0004 (2013.01); A61F 2007/0059 (2013.01); A61H 2015/0014 (2013.01); A61N 7/00 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method of treating meibomian glands having a meibomian gland channel and a meibomian gland orifice at a top of the meibomian gland channel, comprising:
applying regulated heat to an eyelid containing the meibomian glands to reach a temperature adequate to melt at least one obstruction within at least one meibomian gland and place the at least one obstruction in a melted state;
maintaining the regulated heat for a time period adequate to melt the at least one obstruction and place the at least one obstruction in the melted state; and
positioning a pressure application device into direct contact with the eyelid and applying a pressure with the pressure application device over a substantial portion of the eyelid to express the at least one obstruction from the at least one meibomian gland.