US 10,376,230 B2
Obtaining breast density measurements and classifications
Jeffrey C. Wehnes, Richardson, TX (US); Arunkumar Gururajan, Dallas, TX (US); James Monaco, Frisco, TX (US); Ronald Larcom, Frisco, TX (US); and James H. Pike, Carrollton, TX (US)
Assigned to iCad, Inc., Nashua, NH (US)
Appl. No. 15/35,743
Filed by iCAD, Inc., Nashua, NH (US)
PCT Filed Nov. 10, 2014, PCT No. PCT/US2014/064876
§ 371(c)(1), (2) Date May 10, 2016,
PCT Pub. No. WO2015/077076, PCT Pub. Date May 28, 2015.
Claims priority of provisional application 61/906,279, filed on Nov. 19, 2013.
Claims priority of provisional application 61/969,626, filed on Mar. 24, 2014.
Prior Publication US 2016/0256126 A1, Sep. 8, 2016
Int. Cl. G06T 7/00 (2017.01); A61B 6/00 (2006.01); G06T 7/11 (2017.01)
CPC A61B 6/5217 (2013.01) [A61B 6/502 (2013.01); G06T 7/0012 (2013.01); G06T 7/11 (2017.01); G06T 2207/10004 (2013.01); G06T 2207/10116 (2013.01); G06T 2207/30068 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method for breast density computation comprising:
performing, by a processor, breast segmentation on a mammographic image to obtain breast and pectoral muscle segmentation maps;
performing breast thickness correction on the mammographic image to obtain a flattened breast image; and
computing a breast density measurement in accordance with the breast and pectoral muscle segmentation maps and the flattened breast image, wherein computing the breast density measurement in accordance with the breast and pectoral muscle segmentation maps and the flattened breast image comprises:
performing breast density estimation to obtain an initial density map;
performing breast density segmentation on the initial density map to obtain a final density map; and
computing the breast density measurement in accordance with the final density map,
wherein performing breast density segmentation on the initial density map to obtain the final density map comprises:
refining the initial density map to obtain a refined density map, wherein refining the initial density map includes extracting fatty tissue from the initial density map and filling in holes in parenchyma regions of the initial density map;
segmenting the flattened breast image to obtain a flattened-image density map; and
combining the flattened-image density map with the refined density map to obtain the final density map.