US 10,376,143 B2
Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
Peter C. Simpson, Encinitas, CA (US); Robert J. Boock, Carlsbad, CA (US); Mark C. Brister, Encinitas, CA (US); Monica A. Rixman, Medford, MA (US); Kum Ming Woo, San Diego, CA (US); Lisa Nguyen, San Diego, CA (US); Seth R. Brunner, San Diego, CA (US); Arthur Chee, San Diego, CA (US); Melissa A. Nicholas, Monterey, CA (US); Matthew D. Wightlin, San Diego, CA (US); Jack Pryor, San Diego, CA (US); and Dubravka Markovic, San Diego, CA (US)
Assigned to DexCom, Inc., San Diego, CA (US)
Filed by DexCom, Inc., San Diego, CA (US)
Filed on Dec. 31, 2013, as Appl. No. 14/145,404.
Application 14/145,404 is a continuation of application No. 13/732,848, filed on Jan. 2, 2013, granted, now 9,763,609.
Application 13/732,848 is a continuation of application No. 11/750,907, filed on May 18, 2007, granted, now 8,364,229, issued on Jan. 29, 2013.
Application 11/750,907 is a continuation in part of application No. 11/675,063, filed on Feb. 14, 2007, granted, now 7,828,728, issued on Nov. 9, 2010.
Application 11/675,063 is a continuation in part of application No. 11/404,417, filed on Apr. 14, 2006, granted, now 7,613,491, issued on Nov. 3, 2009.
Application 11/404,417 is a continuation in part of application No. 10/896,639, filed on Jul. 21, 2004, granted, now 7,379,765, issued on May 27, 2008.
Application 11/750,907 is a continuation in part of application No. 11/404,417.
Claims priority of provisional application 60/490,009, filed on Jul. 25, 2003.
Prior Publication US 2014/0128703 A1, May 8, 2014
Int. Cl. A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01); A61B 5/1473 (2006.01)
CPC A61B 5/00 (2013.01) [A61B 5/1473 (2013.01); A61B 5/1486 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14735 (2013.01); A61B 5/14865 (2013.01); A61B 5/6848 (2013.01); A61B 5/7203 (2013.01)] 8 Claims
OG exemplary drawing
 
1. An electrochemical continuous glucose sensor configured for implantation in a host, the glucose sensor comprising:
an ex vivo portion and an in vivo portion, wherein the in vivo portion comprises:
a working electrode comprising a plurality of electroactive surfaces each configured to measure a signal indicative of a glucose concentration of a host, wherein the plurality of electroactive surfaces comprise a first electroactive surface, a second electroactive surface, and a third electroactive surface, wherein the plurality of electroactive surfaces are spaced along a substantial length of an in vivo portion of the glucose sensor, wherein the in vivo portion of the glucose sensor comprises a distal end;
a membrane covering at least a portion of the working electrode, wherein the membrane comprises an enzyme configured to react with glucose; and
a reference electrode comprising an electroactive surface, wherein the reference electrode electroactive surface comprises a fourth electroactive surface;
wherein the first electroactive surface, the second electroactive surface, the third electroactive surface, and the fourth electroactive surface share a central axis, wherein the central axis is an axis of sensor insertion, wherein first electroactive surface, the second electroactive surface, and the third electroactive surface are closer to the distal end of the in vivo portion of the sensor than the fourth electroactive surface.