CPC G01N 21/05 (2013.01) [B01L 3/502715 (2013.01); G01N 21/21 (2013.01); G01N 33/54366 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0663 (2013.01); G01N 21/211 (2013.01); G01N 2021/0378 (2013.01); G01N 2021/052 (2013.01)] | 18 Claims |
1. A liquid immersion micro-channel measurement device based on trapezoidal incident structure prism incident-type silicon, the liquid immersion micro-channel measurement device comprising:
a micro-channel structure including a support and at least one micro-channel which is formed on the support and has a sample detecting layer to which a first bioadhesive material is fixed to detect a first sample;
a trapezoidal incident structure prism on an upper portion of the micro-channel structure;
a sample injecting unit which injects a buffer solution including a first sample into the at least one micro-channel;
a polarized light generating unit which irradiates incident light polarized through the trapezoidal incident structure prism onto the at least one micro-channel at an incident angle which satisfies a p-wave non-reflection condition; and
a polarized light detecting unit which detects a polarization change of first reflected light reflected from the sample detecting layer, among polarized incident light;
wherein the trapezoidal incident structure prism totally reflects, from a planarized upper interface of the trapezoidal incident structure prism, second reflected light which is reflected from an interface of a lower interface of the trapezoidal incident structure prism and a buffer solution injected into the at least one micro-channel, among polarized incident light which is incident onto the trapezoidal incident structure prism.
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