CPC C12Q 1/6883 (2013.01) [C12Q 2600/178 (2013.01); G01N 2800/328 (2013.01)] | 18 Claims |
1. A method for treating, inhibiting or ameliorating Kawasaki disease (KD) in a human subject, comprising:
(i) detecting a KD biomarker in a biological sample from a human subject comprising:
(a) providing a population of nucleic acids prepared from the biological sample, wherein the biological sample is enriched for CD31+ exosomes,
(b) hybridizing a probe with the population of nucleic acids, wherein the probe is capable of detecting linc-ZNF337-1, and
(c) detecting the presence of linc-ZNF337-1 in the biological sample,
(d) identifying the subject as having KD when linc-ZNF337-1 is present; and
(ii) administering a therapy for the KD to the subject having KD, wherein the therapy comprises an effective amount of a composition selected from the group consisting of an intravenous immunoglobulin, aspirin, and a corticosteroid.
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