US 11,718,859 B2
Insecticidal proteins and methods for their use
Jennifer Kara Barry, Ames, IA (US); Christian Bartholomay, Madison, WI (US); Louisa D'Lima, San Francisco, CA (US); James J English, San Ramon, CA (US); Kevin Hayes, Urbandale, IA (US); Lu Liu, Palo Alto, CA (US); Amy Lum, Redwood City, CA (US); Brad Poland, Monroe, IA (US); Eric Schepers, Port Deposit, MD (US); Weiping Xie, East Palo Alto, CA (US); Nasser Yalpani, Kelowna (CA); and Genhai Zhu, San Jose, CA (US)
Assigned to PIONEER HI-BRED INTERNATIONAL, INC.; and E. I. DU PONT DE NEMOURS AND COMPANY
Filed by PIONEER HI-BRED INTERNATIONAL, INC., Johnston, IA (US); and E. I. DUPONT DE NEMOURS AND COMPANY, Wilmington, DE (US)
Filed on Dec. 14, 2020, as Appl. No. 17/120,388.
Application 17/120,388 is a division of application No. 16/098,452, granted, now 11,008,585, previously published as PCT/US2017/030602, filed on May 2, 2017.
Claims priority of provisional application 62/331,708, filed on May 4, 2016.
Prior Publication US 2021/0108223 A1, Apr. 15, 2021
Int. Cl. C12N 15/82 (2006.01); C07K 14/21 (2006.01)
CPC C12N 15/8286 (2013.01) [C07K 14/21 (2013.01); Y02A 40/146 (2018.01)] 12 Claims
 
1. A recombinant insecticidal polypeptide having at least 80% sequence identity to the amino acid sequence of SEQ ID NO: 6 or a fragment thereof having insecticidal activity, wherein the insecticidal polypeptide or fragment thereof is joined to a heterologous signal sequence, a transit sequence, or a histidine tag, or fused to a protein of interest either directly or through a linker segment.