CPC C07K 1/165 (2013.01) [B01D 15/327 (2013.01); B01D 15/363 (2013.01); B01D 15/3847 (2013.01); B01J 20/265 (2013.01); B01J 20/286 (2013.01); B01J 20/289 (2013.01); B01J 20/28016 (2013.01); B01J 20/3204 (2013.01); B01J 20/3208 (2013.01); B01J 20/3219 (2013.01); B01J 20/3251 (2013.01); B01J 20/3253 (2013.01); B01J 20/3255 (2013.01); B01J 20/3285 (2013.01); B01J 41/20 (2013.01); C07K 1/36 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); G01N 33/544 (2013.01); B01D 15/3809 (2013.01); B01D 15/3885 (2013.01); B01J 2220/52 (2013.01); B01J 2220/80 (2013.01)] | 15 Claims |
1. A separation matrix comprising a plurality of separation ligands defined by formula (I)
R1-L1-N(R3)-L2-R2 (I)
immobilized on a support via the amine group of formula (I),
wherein R1 is a hydroxyethyl group or a five- or six-membered, substituted or non-substituted ring structure;
L1 is either a methylene group or a covalent bond;
R2 is a five- or six-membered, substituted or non-substituted ring structure;
L2 is either a methylene group or a covalent bond; and
R3 is a methyl group;
wherein said ligands in free form have an octanol-water distribution coefficient (lg P) of 1.8-5;
wherein if R1 is a hydroxyethyl group, L1 is a covalent bond and R2 is a substituted aromatic ring structure or a substituted or non-substituted aliphatic ring structure; and
wherein the separation ligands are defined by formula (IV) or (V):
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