US 11,718,637 B2
Prodrugs of 4′-C-substituted-2-halo-2′- deoxyadenosine nucleosides and methods of making and using the same
Daniel H. Byun, Foster City, CA (US); Byoung-Kwon Chun, Pleasanton, CA (US); Michael O. Clarke, Redwood City, CA (US); Petr Jansa, Foster City, CA (US); Richard L. Mackman, Millbrae, CA (US); Devan Naduthambi, San Bruno, CA (US); and Neil H. Squires, San Francisco, CA (US)
Assigned to Gilead Sciences, Inc., Foster City, CA (US)
Filed by Gilead Sciences, Inc., Foster City, CA (US)
Filed on Mar. 19, 2021, as Appl. No. 17/207,161.
Claims priority of provisional application 62/992,733, filed on Mar. 20, 2020.
Prior Publication US 2022/0363708 A1, Nov. 17, 2022
Int. Cl. A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/16 (2006.01); A61P 31/18 (2006.01); A61K 31/7076 (2006.01); A61K 45/06 (2006.01); C07H 19/20 (2006.01)
CPC C07H 19/16 (2013.01) [A61K 31/7076 (2013.01); A61K 45/06 (2013.01); A61P 31/18 (2018.01); C07H 19/20 (2013.01)] 34 Claims
 
1. A compound of formula:

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.