US 11,718,607 B2
Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst
Ismail K. Warad, Doha (QA); Amjad M. Shraim, Doha (QA); Anas Al-Ali, Nablus (PS); Kifah S M Salih, Doha (QA); Abdelkader Zarrouk, Agdal-Rabat (MA); and Yousef Hijji, Elkridge, MD (US)
Assigned to QATAR UNIVERSITY, Doha (QA)
Filed by QATAR UNIVERSITY, Doha (QA)
Filed on Dec. 30, 2021, as Appl. No. 17/566,248.
Claims priority of provisional application 63/133,113, filed on Dec. 31, 2020.
Prior Publication US 2022/0204487 A1, Jun. 30, 2022
Int. Cl. C07D 409/06 (2006.01); B01J 31/16 (2006.01)
CPC C07D 409/06 (2013.01) [B01J 31/1616 (2013.01)] 22 Claims
 
1. A process for synthesizing (E)-1,2-di(thiophen-2-yl)ethene-1,2-diol from the dimerization of thiophene-2-carbaldehyde in the presence of a Cu(II) catalyst:

OG Complex Work Unit Chemistry