CPC C07D 307/36 (2013.01) [B01J 23/72 (2013.01)] | 16 Claims |
1. A method for preparing a compound of Formula I,
comprising contacting a compound of Formula II,
with a bifunctional copper-based catalyst for selective hydrodeoxygenation of the ketone moiety in the presence of a solvent,
wherein said bifunctional copper-based catalyst is a heterogeneous catalyst selected from the group consisting of 10% Cu/SiO2, 10% Cu/PERLKAT 46-10, 10% Cu/PERLKAT 79-3, 10% Cu/HZSM5, and 10% Cu/zeolite Y,
wherein R is a linear or branched C1-20 alkyl, and
wherein the method is carried out in a continuous flow reactor.
|