US 11,717,790 B2
System for filtration and associated method
Nityananda Maiya, Karnataka (IN); Deepak Aravind, Karnataka (IN); Fredrik Lundström, Uppsala (SE); Saameera Simha Hindupur, Karnataka (IN); Shivakumar Selvaraj, Karnataka (IN); and Alagur Sahebagouda, Karnataka (IN)
Assigned to CYTIVA SWEDEN AB, Uppsala (SE)
Appl. No. 17/252,358
Filed by Cytiva Sweden AB, Uppsala (SE)
PCT Filed Jun. 20, 2019, PCT No. PCT/EP2019/066416
§ 371(c)(1), (2) Date Dec. 15, 2020,
PCT Pub. No. WO2019/243552, PCT Pub. Date Dec. 26, 2019.
Claims priority of application No. 201841023145 (IN), filed on Jun. 21, 2018.
Prior Publication US 2021/0260530 A1, Aug. 26, 2021
Int. Cl. B01D 61/12 (2006.01); B01D 61/22 (2006.01); B01D 65/02 (2006.01)
CPC B01D 61/12 (2013.01) [B01D 61/22 (2013.01); B01D 65/02 (2013.01); B01D 2311/04 (2013.01); B01D 2311/06 (2013.01); B01D 2311/14 (2013.01); B01D 2311/16 (2013.01); B01D 2313/48 (2013.01); B01D 2315/10 (2013.01); B01D 2315/20 (2013.01); B01D 2321/40 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A method of operation of a system comprising a membrane filtration system, the method comprising:
measuring, by a flow sensor, a flow rate of a permeate fluid flowing through a filter of the membrane filtration system;
receiving, by a control unit, a signal indicative of the measured flow rate of the permeate fluid;
determining, by the control unit, a first flux rate of the filter based on the measured flow rate signal of the permeate fluid;
comparing, by the control unit, the first flux rate with a first predetermined flux rate;
operating the membrane filtration system, by the control unit, in a normal filtration mode in response to the first flux rate being greater than or equal to the first predetermined flux rate;
operating the membrane filtration system, by the control unit, in (i) a modified filtration mode or (ii) a cleaning mode in response to the first flux rate being less than the first predetermined flux rate, wherein the cleaning mode of the membrane filtration system is further based on a determined normalized water permeability value of the filter; and
resetting the first predetermined flux rate in accordance with a change in transmembrane pressure (TMP) when the filter is operated over a number of cycles until the determined normalized water permeability value of the filter is less than a predetermined percentage of a predetermined base value of the filter.