US 11,717,662 B2
Sonotrode
Alexander Britva, Migdal Ha'emek (IL); Alexander Dverin, Netanya (IL); Yevgeny Pens, Haifa (IL); and Ziv Karni, Kfar Shmaryahu (IL)
Assigned to Alma Lasers Ltd.
Filed by ALMA LASERS LTD., Caesarea (IL)
Filed on Feb. 13, 2019, as Appl. No. 16/274,284.
Application 16/274,284 is a continuation of application No. 13/386,949, granted, now 10,238,849, previously published as PCT/IB2010/053474, filed on Jul. 30, 2010.
Claims priority of provisional application 61/229,817, filed on Jul. 30, 2009.
Prior Publication US 2019/0167963 A1, Jun. 6, 2019
This patent is subject to a terminal disclaimer.
Int. Cl. A61M 37/00 (2006.01); A61B 17/00 (2006.01)
CPC A61M 37/0092 (2013.01) [A61B 2017/00765 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A sonotrode for transmitting acoustic energy from an ultrasound generator to a substrate, for use in transdermal delivery of therapeutic or cosmetic compounds, the sonotrode comprising a proximal portion to be coupled in use to the ultrasound generator and a neck portion coupled at one end to the proximal portion and terminating at a distal end in a flared foot portion,
acoustic energy from the ultrasound generator being applied in use to the substrate by transmission of ultrasound through the proximal portion, the neck and the foot portion,
wherein a total effective length of the sonotrode is substantially equal to one third of a wavelength of the acoustic energy applied to the sonotrode from the ultrasound generator, and
whereby a maximum amplitude of an acoustic energy wave is focused below a surface of the skin.