US 11,717,528 B2
Methods and compositions relating to the treatment of fibrosis
Jack A. Elias, Providence, RI (US); Chun Geun Lee, Woodbridge, CT (US); and Chang-Min Lee, Warwick, RI (US)
Assigned to BROWN UNIVERSITY, Providence, RI (US)
Filed by BROWN UNIVERSITY, Providence, RI (US)
Filed on Jan. 7, 2022, as Appl. No. 17/571,295.
Application 17/571,295 is a continuation of application No. 16/639,462, granted, now 11,219,630, previously published as PCT/US2018/046845, filed on Aug. 17, 2018.
Claims priority of provisional application 62/546,687, filed on Aug. 17, 2017.
Prior Publication US 2022/0117987 A1, Apr. 21, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/7034 (2006.01)
CPC A61K 31/7034 (2013.01) 5 Claims
 
1. A method of treating pulmonary fibrosis in a subject in need thereof, the method comprising administering kasugamycin or derivatives thereof to the subject, wherein the subject has been determined to have an increased level of Chit1 and/or Chit1 activity.