	US 11,717,516 B2
	Co-crystals
Daniel G. Chain, New York, NY (US); and Ronald Mueller, Northbrook, IL (US)
Assigned to CereSpir Incorporated, New York, NY (US)
Filed by CereSpir Incorporated, New York, NY (US)
Filed on Oct. 25, 2022, as Appl. No. 17/973,297.
Application 17/973,297 is a continuation of application No. 17/897,388, filed on Aug. 29, 2022.
Claims priority of provisional application 63/238,928, filed on Aug. 31, 2021.
Prior Publication US 2023/0116520 A1, Apr. 13, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/455 (2006.01); A61K 31/192 (2006.01)

CPC A61K 31/455 (2013.01) [A61K 31/192 (2013.01)]

11 Claims

1. A co-crystal comprising itanapraced and a coformer, wherein the coformer is nicotinamide and the co-crystal has an X-ray Powder Diffraction Pattern (XRPD) with specific peaks, expressed in 2⊖ produced from a Cu radiation source (λ=1.54 Å after Ni filtering), at about 14.63°; 14.90°; 15.56°; 16.71°; 18.24°; 18.46°; 20.03°; 20.27°; 22.01°; 22.27; 24.17; 24.47; 26.14; 26.47; 27.83; 28.85; 29.97; 30.64; 32.42; 34.07; and 39.14°, all +/−0.2 degrees 2⊖.