CPC C12N 15/113 (2013.01) [C12N 2310/18 (2013.01); C12N 2310/531 (2013.01)] | 20 Claims |
1. A ribonucleic acid (RNA) duplex comprising a synthetic first RNA sequence that provides exonuclease resistance to the RNA duplex when hybridized to a heterologous second RNA sequence without exonuclease resistance, wherein a region of said synthetic RNA sequence and a region of said heterologous RNA sequence hybridize to form an interwoven pseudoknot structure, wherein the synthetic first RNA sequence that provides exonuclease resistance to the RNA duplex comprises a sequence of nucleotides 10-60 of SEQ ID NO:2.
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