US 11,713,336 B2
Peptides and nanoparticles for intracellular delivery of molecules
Gilles Divita, St André de Sangonis (FR); and Neil Desai, Pacific Palisades, CA (US)
Assigned to Aadigen, LLC, Pacific Palisades, CA (US)
Filed by AADIGEN, LLC, Pacific Palisades, CA (US)
Filed on Jul. 15, 2020, as Appl. No. 16/930,091.
Application 16/930,091 is a continuation of application No. 15/539,619, granted, now 10,745,440, previously published as PCT/EP2015/081197, filed on Dec. 23, 2015.
Claims priority of application No. 1403004 (FR), filed on Dec. 24, 2014.
Prior Publication US 2021/0032290 A1, Feb. 4, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. C07K 7/08 (2006.01); C12N 15/87 (2006.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01); A61K 38/00 (2006.01)
CPC C07K 7/08 (2013.01) [A61K 31/713 (2013.01); A61K 47/64 (2017.08); A61K 47/6929 (2017.08); C12N 15/113 (2013.01); C12N 15/1137 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/141 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01)] 25 Claims
 
1. A non-naturally occurring peptide comprising the amino acid sequence RWRLWRX1X2X3X4SR (SEQ ID NO: 6), and wherein X1 is V or S, X2 is R, V, or A, X3 is S or L, and X4 is W or Y.