US 11,712,660 B2
Dialysis cell for sample preparation for a chemical analysis method
Markus Läubli, Herisau (CH); Wolfgang Frenzel, Berlin (DE); Inga Markeviciute, Berlin (DE); and Daniel Abderhalden, Waldkirch (CH)
Assigned to Metrohm AG, Herisau (CH)
Appl. No. 16/637,804
Filed by METROHM AG, Herisau (CH)
PCT Filed Aug. 10, 2018, PCT No. PCT/EP2018/071821
§ 371(c)(1), (2) Date Feb. 10, 2020,
PCT Pub. No. WO2019/030404, PCT Pub. Date Feb. 14, 2019.
Claims priority of application No. 17185845 (EP), filed on Aug. 11, 2017.
Prior Publication US 2020/0215488 A1, Jul. 9, 2020
Int. Cl. B01D 61/24 (2006.01); B01D 61/28 (2006.01); B01D 63/08 (2006.01); B01D 71/14 (2006.01); B01D 71/34 (2006.01); B01D 71/50 (2006.01); G01N 1/34 (2006.01); G01N 30/14 (2006.01); G01N 1/40 (2006.01); G01N 30/02 (2006.01); A61M 1/16 (2006.01); A61M 1/14 (2006.01)
CPC B01D 61/243 (2013.01) [B01D 61/28 (2013.01); B01D 63/087 (2013.01); B01D 71/14 (2013.01); B01D 71/34 (2013.01); B01D 71/50 (2013.01); G01N 1/34 (2013.01); G01N 30/14 (2013.01); A61M 1/14 (2013.01); A61M 1/16 (2013.01); B01D 2311/26 (2013.01); B01D 2313/28 (2013.01); B01D 2313/30 (2013.01); G01N 2001/4016 (2013.01); G01N 2030/027 (2013.01); G01N 2030/146 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A dialysis cell for sample preparation for a chromatographic method comprising:
a donor channel; and
a parallelly running acceptor channel,
wherein, when used as intended, the donor channel and the acceptor channel are separated from one another by a selectively permeable dialysis membrane,
wherein the acceptor channel has, on its entire length, a volume VA which is smaller than a parallelly running volume VD of the donor channel,
wherein the donor channel and the acceptor channel are spiral or meandering,
wherein the dialysis cell comprises two half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are formed as, in each case, an indentation in a contact surface of one of the half-cells with the dialysis membrane, and
wherein at least one support element is formed in the acceptor channel, which support element spaces the dialysis membrane from the side of the acceptor channel that faces away from the dialysis membrane.