US 11,712,467 B2
Methods of rational nicotine hapten design and uses thereof
Yung Chang, Tempe, AZ (US); Sidney Hecht, Phoenix, AZ (US); Joseph Leal, Phoenix, AZ (US); Viswanath Arutla, Tempe, AZ (US); Xiaowei Liu, Tempe, AZ (US); and Sriram Sokalingam, Tempe, AZ (US)
Assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US)
Filed by ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US)
Filed on May 12, 2022, as Appl. No. 17/743,058.
Application 15/863,118 is a division of application No. 15/189,930, filed on Jun. 22, 2016, granted, now 9,884,114, issued on Feb. 6, 2018.
Application 17/743,058 is a continuation of application No. 15/863,118, filed on Jan. 5, 2018, granted, now 11,357,848.
Claims priority of provisional application 62/183,445, filed on Jun. 23, 2015.
Prior Publication US 2022/0362375 A1, Nov. 17, 2022
Int. Cl. A61K 39/385 (2006.01); G16B 15/00 (2019.01); G16B 20/30 (2019.01); G16B 20/00 (2019.01); C07D 401/14 (2006.01); A61K 47/64 (2017.01); G01N 33/94 (2006.01); A61K 39/00 (2006.01); G16B 15/30 (2019.01)
CPC A61K 39/385 (2013.01) [A61K 39/0013 (2013.01); A61K 47/646 (2017.08); C07D 401/14 (2013.01); G01N 33/946 (2013.01); G16B 15/00 (2019.02); G16B 15/30 (2019.02); G16B 20/00 (2019.02); G16B 20/30 (2019.02); A61K 2039/6012 (2013.01)] 13 Claims
 
1. A method for eliciting an immune response in a subject, the method comprising:
administering to the subject a composition comprising a nicotine hapten conjugate, wherein the nicotine hapten is selected from the group consisting of:

OG Complex Work Unit Chemistry