US 11,710,238 B2
Plaque segmentation in intravascular optical coherence tomography (OCT) images using deep learning
David L. Wilson, Cleveland Heights, OH (US); Yazan Gharaibeh, Shaker Heights, OH (US); David Prabhu, Dublin, OH (US); Juhwan Lee, Westlake, OH (US); and Chaitanya Kolluru, Cleveland Heights, OH (US)
Assigned to Case Western Reserve University, Cleveland, OH (US)
Filed by Case Western Reserve University, Cleveland, OH (US)
Filed on Aug. 24, 2020, as Appl. No. 17/1,126.
Claims priority of provisional application 62/925,311, filed on Oct. 24, 2019.
Prior Publication US 2021/0125337 A1, Apr. 29, 2021
Int. Cl. G06T 7/11 (2017.01); G06T 7/155 (2017.01); G06T 5/00 (2006.01); G06T 5/20 (2006.01); G06T 7/00 (2017.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01); G06N 20/00 (2019.01); G06N 3/08 (2023.01); G16H 20/00 (2018.01)
CPC G06T 7/11 (2017.01) [G06N 3/08 (2013.01); G06N 20/00 (2019.01); G06T 5/002 (2013.01); G06T 5/20 (2013.01); G06T 7/0012 (2013.01); G06T 7/155 (2017.01); G16H 20/00 (2018.01); G16H 30/40 (2018.01); G16H 50/30 (2018.01); G06T 2207/10101 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/30101 (2013.01)] 23 Claims
OG exemplary drawing
 
1. A non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, comprising:
accessing vascular imaging data for a patient, wherein the vascular imaging data comprises a volume of interest;
pre-processing the vascular imaging data to generate pre-processed vascular imaging data;
providing the pre-processed vascular imaging data to a deep learning model trained to segment a lumen and a vascular plaque;
obtaining segmented vascular imaging data from the deep learning model, wherein the segmented vascular imaging data comprises a segmented lumen and a segmented vascular plaque in the volume of interest;
computing one or more plaque attributes associated with the segmented vascular plaque, wherein the one or more plaque attributes comprise a plaque thickness, a plaque depth, and a plaque arc angle; and
generating a score based on one or more plaque attributes of the segmented vascular plaque, wherein the score is indicative of whether or not the segmented vascular plaque will limit stent expansion.