CPC C12Q 1/6883 (2013.01) [A61K 31/22 (2013.01); A61K 31/225 (2013.01); C07K 16/28 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/172 (2013.01); G01N 2800/32 (2013.01); G01N 2800/324 (2013.01)] | 14 Claims |
1. A method for reducing the risk of myocardial infarction in a human, the method comprising:
a) testing nucleic acid from said human for a polymorphism in gene NPC1 as represented by position 101 of SEQ ID NO:59198 or its complement by contacting said nucleic acid with an oligonucleotide that specifically hybridizes to G at said position 101 of SEQ ID NO:59198 or C at said complement;
b) detecting said G or said C;
c) identifying said human as having an increased risk for myocardial infarction or as being responsive to statin treatment for reducing their risk of myocardial infarction due to the presence of said G or said C; and
d) administering a statin to said human.
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