US 11,707,212 B2
Microdialysis device comprising attachment sheet
Pernilla Abrahamsson, Umeå (SE); Robert Herz, Plauen (DE); Einar Pontén, Söderåkra (SE); and Bjoern Glaesel, Kirchenlamitz (DE)
Assigned to SENZIME AB (PUBL.), Uppsala (SE)
Filed by Senzime AB (publ.), Uppsala (SE)
Filed on Jan. 8, 2021, as Appl. No. 17/145,078.
Application 17/145,078 is a continuation of application No. 15/755,526, granted, now 10,966,641, previously published as PCT/EP2016/070634, filed on Sep. 1, 2016.
Claims priority of application No. 1551133-0 (SE), filed on Sep. 4, 2015.
Prior Publication US 2021/0145326 A1, May 20, 2021
Int. Cl. A61B 5/145 (2006.01); A61B 5/00 (2006.01); A61M 25/02 (2006.01); A61M 1/16 (2006.01)
CPC A61B 5/14528 (2013.01) [A61B 5/688 (2013.01); A61M 25/02 (2013.01); A61B 5/6852 (2013.01); A61M 1/1678 (2013.01); A61M 2209/088 (2013.01)] 16 Claims
OG exemplary drawing
 
1. An elongated microdialysis device (1) comprising a distal part (2) and a proximal part (3), said proximal part (3) comprising an inlet (4) and an outlet (5), said inlet (4) and outlet (5) adapted to allow a fluid to flow through said microdialysis device (1) from said inlet (4) through said proximal part (3) via said distal part (2) and back to said outlet (5), along substantially an entire length of said microdialysis device (1),
wherein said distal part (2) of said microdialysis device (1) is configured for temporary attachment and/or placement on a surface of a human or animal organ, and said distal part (2) comprises a probe (2) for sampling substances present on said surface of said organ and indicating a condition of said organ, said probe comprising
an inlet channel (10) adapted to receive fluid originating from said inlet (4),
an outlet channel (11) adapted to receive fluid originating from said inlet channel (10),
wherein at least part of an outer surface (12) of said probe (2) is adapted to be placed on said surface of an organ, said part of the outer surface of said probe comprising a semi-permeable material (13, 23) adapted to allow passage of substances from the outside of said probe through said semi-permeable material (13, 23) into said fluid within said microdialysis device (1), characterized in that said device further comprises an attachment sheet (14), said attachment sheet (14) being configured to facilitate placement and/or attachment of said probe (2) to said organ surface, the side of the probe (2) comprising the semi-permeable material (13) being adapted to lie against said organ surface,
wherein said attachment sheet is adapted to be arranged essentially flat against the organ surface when said distal part (2) is arranged on a surface of a human or animal organ, said attachment sheet (14) comprising an opening essentially corresponding to said part of the outer surface comprising the semi-permeable material (13, 23), and
wherein said attachment sheet is made of a substantially fluid-tight material and blocks access to said semi-permeable material by surrounding fluids when the probe is attached to a surface by the attachment sheet.